Thermal Cycle

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PC Machines or Thermal Cyclers are used to biotechnological and medical laboratories to amplify segments of DNA via the polymerase chain reaction (PCR) process. The instrument has a thermal block with holes where tubes holding the PCR reaction mixtures can be inserted. The cycler then raises and lowers the temperature of the block in discrete, per-programmed steps. This instrument helps in heating and cooling a DNA sample in order to perform the PCR.

Today, there are numerous Thermal Cyclers available from a variety of vendors and manufacturers. The instruments differ in the number of samples that can be handled, the size of reaction tube used, the speed of temperature change, and cost.